2055041-17-1

2055041-17-1 structure

2055041-17-1 structure

Name: Propargyl-PEG4-S-PEG4-propargyl
Chemical Name: Propargyl-PEG4-S-PEG4-propargyl
CAS Number: 2055041-17-1
Molecular Formula: C₂₂H₃₈O₈S
Molecular Weight: 462.60
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 15:23:57
Modify Date: 2024-01-09 19:52:18
Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG4-S-PEG4-propargyl
Synonyms	MFCD29918246

Description	Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₂H₃₈O₈S
Molecular Weight	462.60