2055041-20-6

2055041-20-6 structure
2055041-20-6 structure
  • Name: Propargyl-PEG4-S-PEG4-acid
  • Chemical Name: Propargyl-PEG4-S-PEG4-acid
  • CAS Number: 2055041-20-6
  • Molecular Formula: C22H40O10S
  • Molecular Weight: 496.61
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:40:33
  • Modify Date: 2024-01-08 09:16:26
  • Propargyl-PEG4-S-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG4-S-PEG4-acid
Synonyms MFCD29918242
Description Propargyl-PEG4-S-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C22H40O10S
Molecular Weight 496.61