Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TCO-PEG9-maleimide
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

2183440-37-9

2183440-37-9 structure

2183440-37-9 structure

Name: TCO-PEG9-maleimide
Chemical Name: TCO-PEG9-maleimide
CAS Number: 2183440-37-9
Molecular Formula: C₃₆H₆₁N₃O₁₄
Molecular Weight: 759.88
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 13:47:23
Modify Date: 2024-01-04 19:40:08
TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	TCO-PEG9-maleimide

Description	TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₆H₆₁N₃O₁₄
Molecular Weight	759.88