TCO-PEG9-maleimide

Modify Date: 2024-01-04 19:40:08

TCO-PEG9-maleimide structure	Common Name	TCO-PEG9-maleimide
	CAS Number	2183440-37-9	Molecular Weight	759.88
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₆H₆₁N₃O₁₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TCO-PEG9-maleimide

TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	TCO-PEG9-maleimide

Description	TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₆H₆₁N₃O₁₄
Molecular Weight	759.88

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TCO-PEG9-maleimide
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Purity: 95.0%
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