2247890-13-5
2247890-13-5 structure
- Name: BAY 6035
- Chemical Name: BAY-6035
- CAS Number: 2247890-13-5
- Molecular Formula: C22H28N4O3
- Molecular Weight: 396.48
- Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
- Create Date: 2020-08-11 14:37:32
- Modify Date: 2024-09-18 14:34:28
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BAY-6035 is a potent, selective and substrate-competitive inhibitor of SMYD3. BAY-6035 inhibits methylation of MEKK2 peptide with an IC50 of 88 nM[1].
| Name | BAY-6035 |
|---|
| Description | BAY-6035 is a potent, selective and substrate-competitive inhibitor of SMYD3. BAY-6035 inhibits methylation of MEKK2 peptide with an IC50 of 88 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
SMYD3:88 nM (IC50) |
| In Vitro | BAY-6035 inhibits in vitro methylation of MEKK2 peptide with an IC50 of 88 nM and has more than 100-fold selectivity over other histone methyltransferases[1]. BAY-6035 inhibits the methylation of MEKK2 in cells with an IC50 of 70 nM[1]. |
| References |
| Molecular Formula | C22H28N4O3 |
|---|---|
| Molecular Weight | 396.48 |