1600543-88-1

1600543-88-1 structure

Name: Huwentoxin XVI TFA
Chemical Name: Huwentoxin XVI
CAS Number: 1600543-88-1
Molecular Formula: C₁₉₆H₂₉₂N₅₀O₅₆S₆
Molecular Weight: 4437.13
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2020-08-08 12:35:27
Modify Date: 2024-01-08 14:14:08
Huwentoxin XVI, an analgesic, is a highly reversible and selective mammalian N-type calcium channel (IC50 of ~60 nM) antagonist from Chinese tarantula Ornithoctonus huwena. Huwentoxin XVI has no effect on voltagegated T-type calcium channels, potassium channels or sodium channels[1].

Name	Huwentoxin XVI

Description	Huwentoxin XVI, an analgesic, is a highly reversible and selective mammalian N-type calcium channel (IC50 of ~60 nM) antagonist from Chinese tarantula Ornithoctonus huwena. Huwentoxin XVI has no effect on voltagegated T-type calcium channels, potassium channels or sodium channels[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Neurological Disease
Target	IC50: ~60 nM (N-type calcium channel)[1]
References	[1]. Meichun Deng, et al. Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena. Neuropharmacology. 2014 Apr;79:657-67.

Molecular Formula	C₁₉₆H₂₉₂N₅₀O₅₆S₆
Molecular Weight	4437.13