1198080-03-3

1198080-03-3 structure

Name: Propargyl-PEG6-N3
Chemical Name: 1-Azido-3,6,9,12,15,18-hexaoxahenicos-20-yne
CAS Number: 1198080-03-3
Molecular Formula: C₁₅H₂₇N₃O₆
Molecular Weight: 345.391
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2021-01-10 09:22:32
Modify Date: 2024-04-09 00:06:56
Propargyl-PEG6-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1-Azido-3,6,9,12,15,18-hexaoxahenicos-20-yne
Synonyms	1-Azido-3,6,9,12,15,18-hexaoxahenicos-20-yne 3,6,9,12,15,18-Hexaoxaheneicos-20-yne, 1-azido-

Description	Propargyl-PEG6-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562