1973383-30-0

1973383-30-0 structure
1973383-30-0 structure
  • Name: Propargyl-PEG6-Br
  • Chemical Name: Propargyl-PEG6-Br
  • CAS Number: 1973383-30-0
  • Molecular Formula: C15H27BrO6
  • Molecular Weight: 383.28
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-11 16:48:35
  • Modify Date: 2024-01-08 13:49:15
  • Propargyl-PEG6-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG6-Br
Synonyms MFCD32263749
Description Propargyl-PEG6-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H27BrO6
Molecular Weight 383.28