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170304-76-4

170304-76-4 structure
170304-76-4 structure
  • Name: Cl-PEG2-acid
  • Chemical Name: Cl-PEG2-acid
  • CAS Number: 170304-76-4
  • Molecular Formula: C6H11ClO4
  • Molecular Weight: 182.60
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-06-08 23:17:30
  • Modify Date: 2024-01-09 10:44:07
  • Cl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Cl-PEG2-acid
Synonyms MFCD20623441
Description Cl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C6H11ClO4
Molecular Weight 182.60
Hazard Codes Xi