9026-30-6

9026-30-6 structure

Name: poly(a) polymerase
Chemical Name: poly(a) polymerase
CAS Number: 9026-30-6
Molecular Formula:
Molecular Weight:
Create Date: 2021-09-11 11:27:26
Modify Date: 2024-01-09 07:39:51
Poly(A) polymerase catalyzes the incorporation of ATP into the RNA 3' end in the form of AMP, that is, adding a polyadenosine tail at the RNA 3' end. Poly(A) polymerase increases RNA stability and increases mRNA translation efficiency in eukaryotic cells. Poly(A) polymerase has high tailing efficiency and can add 20-200 A bases to the 3' end of RNA[1][2].

Name	poly(a) polymerase

Description	Poly(A) polymerase catalyzes the incorporation of ATP into the RNA 3' end in the form of AMP, that is, adding a polyadenosine tail at the RNA 3' end. Poly(A) polymerase increases RNA stability and increases mRNA translation efficiency in eukaryotic cells. Poly(A) polymerase has high tailing efficiency and can add 20-200 A bases to the 3' end of RNA[1][2].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Others
References	[1]. Li W, et al. The novel poly(A) polymerase Star-PAP is a signal-regulated switch at the 3'-end of mRNAs. Adv Biol Regul. 2013 Jan;53(1):64-76. [2]. Chen LS, et al. Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues. Biochem Pharmacol. 2010 Mar 1;79(5):669-77.

Appearance	buffered aqueous glycerol solution
Storage condition	−20°C

Safety Phrases	23-24/25
WGK Germany	3