2648089-95-4

2648089-95-4 structure

Name: AT-9010 triethylamine
Chemical Name: AT-9010 triethylamine
CAS Number: 2648089-95-4
Molecular Formula: C₃₅H₇₇FN₉O₁₃P₃
Molecular Weight: 943.96
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2021-09-09 13:03:39
Modify Date: 2024-01-06 19:43:19
AT-9010 triethylamine, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 triethylamine can inhibit SARS-CoV-2 replication[1].

Name	AT-9010 triethylamine

Description	AT-9010 triethylamine, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 triethylamine can inhibit SARS-CoV-2 replication[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	NiRAN[1]
In Vitro	Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1].
In Vivo	SARS-CoV-2抑制剂
References	[1]. Atea Pharmaceuticals Announces Publication of Preclinical Data Highlighting Potent Activity of AT-527 Against SARS-CoV-2. BOSTON, Feb. 08, 2021. Atea Pharmaceuticals, Inc.

Molecular Formula	C₃₅H₇₇FN₉O₁₃P₃
Molecular Weight	943.96

Hazard Codes	Xi