Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AT-9010
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: AT-9010
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

1261253-79-5

1261253-79-5 structure

1261253-79-5 structure

Name: AT-9010
Chemical Name: AT-9010
CAS Number: 1261253-79-5
Molecular Formula: C₁₁H₁₇FN₅O₁₃P₃
Molecular Weight: 539.20
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2021-09-12 21:07:19
Modify Date: 2024-01-09 08:55:05
AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 can inhibit SARS-CoV-2 replication[1].

Name	AT-9010

Description	AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 can inhibit SARS-CoV-2 replication[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	NiRAN[1]
In Vitro	Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1].
References	[1]. Atea Pharmaceuticals Announces Publication of Preclinical Data Highlighting Potent Activity of AT-527 Against SARS-CoV-2. BOSTON, Feb. 08, 2021. Atea Pharmaceuticals, Inc.

Molecular Formula	C₁₁H₁₇FN₅O₁₃P₃
Molecular Weight	539.20

Hazard Codes	Xi