- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: (RS)-AMPA monohydrate
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Huang
- DC Chemicals Limited
- China
- Product Name: (RS)-AMPA monohydrate
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Cao
76463-67-7
76463-67-7 structure
- Name: (RS)-AMPA monohydrate
- Chemical Name: (RS)-AMPA monohydrate
- CAS Number: 76463-67-7
- Molecular Formula: C7H12N2O5
- Molecular Weight: 204.18
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
- Create Date: 2021-09-27 21:22:57
- Modify Date: 2024-01-08 17:33:07
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(RS)-AMPA ((±)-AMPA) monohydrate is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA monohydrate does not interfere with binding sites for kainic acid or NMDA receptors[1][2].
| Name | (RS)-AMPA monohydrate |
|---|
| Description | (RS)-AMPA ((±)-AMPA) monohydrate is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA monohydrate does not interfere with binding sites for kainic acid or NMDA receptors[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | (RS)-AMPA monohydrate (10-3-10-4 M) causes depolarizations of cultured rat spinal and brainstem neurones. The depolarization by (RS)-AMPA monohydrate is clearly dose-dependent, although there is a great variability of effects between individual neurones. Application of (RS)-AMPA monohydrate at 10-5 M produces only small depolarizations (3-7 mV), whereas at 10-4 M, the amplitudes of the depolarizations ranged from 4 to 33 mV. (RS)-AMPA monohydrate also causes an increase of the discharge rate of spontaneously firing neurones or sometimes evoked a short burst of action potentials in silent cells. (RS)-AMPA monohydrate exerts its depolarizing effects by activating glutamate/quisqualate receptors without affecting NMDA receptors[1]. |
| References |
| Molecular Formula | C7H12N2O5 |
|---|---|
| Molecular Weight | 204.18 |