1246833-02-2

1246833-02-2 structure

1246833-02-2 structure

Name: Teludipine-d6
Chemical Name: Teludipine-d6
CAS Number: 1246833-02-2
Molecular Formula: C₂₈H₃₂D₆N₂O₆
Molecular Weight: 504.65
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2021-10-08 17:58:52
Modify Date: 2024-01-09 19:15:38
Teludipine-d6 (GR53992B-d6) is the deuterium labeled Teludipine hydrochloride. Teludipine is a lipophilic calcium channel blocker[1][2].

Name	Teludipine-d6

Description	Teludipine-d6 (GR53992B-d6) is the deuterium labeled Teludipine hydrochloride. Teludipine is a lipophilic calcium channel blocker[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Cancer
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Tolomeo M, et al. Effects of R-enantiomer (GR66234A) and L-enantiomer (GR66235A) of telupidine, a new dihydropyridine derivative, on cell lines displaying the multidrug resistant phenotype. Haematologica. 1994 Jul-Aug;79(4):328-33.

Molecular Formula	C₂₈H₃₂D₆N₂O₆
Molecular Weight	504.65