2722635-28-9

2722635-28-9 structure
2722635-28-9 structure
  • Name: SARS-CoV-2-IN-11
  • Chemical Name: SARS-CoV-2-IN-11
  • CAS Number: 2722635-28-9
  • Molecular Formula: C27H38F2N3NaO8S
  • Molecular Weight: 625.66
  • Catalog: Signaling Pathways Anti-infection SARS-CoV
  • Create Date: 2022-03-14 09:05:04
  • Modify Date: 2024-01-05 18:13:46
  • SARS-CoV-2-IN-11 is a potent and nontoxic inhibitor of SARS-CoV-2 3CL protease (3CLpro) with an IC50 and EC50 of 0.17 and 1.45 nM, respectively. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for therapeutic intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals[1].

Name SARS-CoV-2-IN-11
Description SARS-CoV-2-IN-11 is a potent and nontoxic inhibitor of SARS-CoV-2 3CL protease (3CLpro) with an IC50 and EC50 of 0.17 and 1.45 nM, respectively. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for therapeutic intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals[1].
Related Catalog
Target

SARS-CoV-2 3C-like proteas[1]

References

[1]. Dampalla CS, et al. Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies. J Med Chem. 2021;64(24):17846-17865.

Molecular Formula C27H38F2N3NaO8S
Molecular Weight 625.66