2722634-95-7

2722634-95-7 structure

Name: SARS-CoV-2-IN-10
Chemical Name: SARS-CoV-2-IN-10
CAS Number: 2722634-95-7
Molecular Formula: C₂₇H₃₇F₂N₃O₅
Molecular Weight: 521.60
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2022-03-14 17:56:15
Modify Date: 2024-01-30 12:43:28
SARS-CoV-2-IN-10 is a potent and nontoxic inhibitor of SARS-CoV-2 3CL protease (3CLpro) with an IC50 and EC50 of 0.13 and 1.03 nM, respectively. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for therapeutic intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals[1].

Name	SARS-CoV-2-IN-10

Description	SARS-CoV-2-IN-10 is a potent and nontoxic inhibitor of SARS-CoV-2 3CL protease (3CLpro) with an IC50 and EC50 of 0.13 and 1.03 nM, respectively. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for therapeutic intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	SARS-CoV-2 3C-like proteas[1]
References	[1]. Dampalla CS, et al. Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies. J Med Chem. 2021;64(24):17846-17865.

Molecular Formula	C₂₇H₃₇F₂N₃O₅
Molecular Weight	521.60