SARS-CoV-2-IN-10

Modify Date: 2024-01-30 12:43:28

SARS-CoV-2-IN-10 Structure
SARS-CoV-2-IN-10 structure
Common Name SARS-CoV-2-IN-10
CAS Number 2722634-95-7 Molecular Weight 521.60
Density N/A Boiling Point N/A
Molecular Formula C27H37F2N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SARS-CoV-2-IN-10


SARS-CoV-2-IN-10 is a potent and nontoxic inhibitor of SARS-CoV-2 3CL protease (3CLpro) with an IC50 and EC50 of 0.13 and 1.03 nM, respectively. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for therapeutic intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals[1].

 Names

Name SARS-CoV-2-IN-10

 SARS-CoV-2-IN-10 Biological Activity

Description SARS-CoV-2-IN-10 is a potent and nontoxic inhibitor of SARS-CoV-2 3CL protease (3CLpro) with an IC50 and EC50 of 0.13 and 1.03 nM, respectively. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for therapeutic intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals[1].
Related Catalog
Target

SARS-CoV-2 3C-like proteas[1]

References

[1]. Dampalla CS, et al. Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies. J Med Chem. 2021;64(24):17846-17865.

 Chemical & Physical Properties

Molecular Formula C27H37F2N3O5
Molecular Weight 521.60
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