2296708-07-9

2296708-07-9 structure

2296708-07-9 structure

Name: 3,4-Dibromo-Mal-PEG2-amine TFA
Chemical Name: 3,4-Dibromo-Mal-PEG2-amine TFA
CAS Number: 2296708-07-9
Molecular Formula: C₁₂H₁₅Br₂F₃N₂O₆
Molecular Weight: 500.06
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2022-03-27 11:50:23
Modify Date: 2024-01-02 13:10:22
3,4-Dibromo-Mal-PEG2-amine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	3,4-Dibromo-Mal-PEG2-amine TFA

Description	3,4-Dibromo-Mal-PEG2-amine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₂H₁₅Br₂F₃N₂O₆
Molecular Weight	500.06