Name | APJ receptor agonist 5 |
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Description | APJ receptor agonist 5 (compound 3) is a potent and orally active agonist of apelin receptor (APJ) with an EC50 of 0.4 nM. APJ receptor agonist 5 displays excellent pharmacokinetic profiles in the rodent heart failure (HF) model. APJ receptor agonist 5 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 leads to improved cardiac function and can be used for researching the HF disease[1]. |
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Related Catalog | |
References |
Molecular Formula | C26H29N3O6 |
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Molecular Weight | 479.52 |