1635437-52-3

1635437-52-3 structure

Name: Biotinylated-JQ1
Chemical Name: Biotinylated-JQ1
CAS Number: 1635437-52-3
Molecular Formula: C₃₉H₅₃ClN₈O₆S₂
Molecular Weight: 829.47
Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
Create Date: 2022-05-02 17:49:52
Modify Date: 2024-01-09 12:12:10
Biotinylated-JQ1 (Biotin-JQ1) is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM[1].

Name	Biotinylated-JQ1

Description	Biotinylated-JQ1 (Biotin-JQ1) is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
In Vitro	Biotinylated-JQ1 (0.1 nM-100 μM; 72 hours) inhibits MM1.S cell proliferation with an EC50 of 0.4 μM[1].
References	[1]. Lars Anders, et al. Genome-wide localization of small molecules. Nat Biotechnol. 2014 Jan;32(1):92-6.

Molecular Formula	C₃₉H₅₃ClN₈O₆S₂
Molecular Weight	829.47