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2374827-31-1

2374827-31-1 structure
2374827-31-1 structure
  • Name: DCN1-UBC12-IN-1
  • Chemical Name: DCN1-UBC12-IN-1
  • CAS Number: 2374827-31-1
  • Molecular Formula: C24H23N7O3S2
  • Molecular Weight: 521.61
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease E1/E2/E3 Enzyme
  • Create Date: 2022-04-07 19:36:54
  • Modify Date: 2024-01-06 18:46:52
  • DCN1-UBC12-IN-1 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.86 nM. Anticardiac fibrotic effect[1].

Name DCN1-UBC12-IN-1
Description DCN1-UBC12-IN-1 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.86 nM. Anticardiac fibrotic effect[1].
Related Catalog
In Vitro DCN1-UBC12-IN-1 (compound 44) possesses low cytotoxicity toward cardiac fibroblasts (CFs) with an IC50 of 9.97 μM for 24 h[1].
References

[1]. He ZX, et al. Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects. J Med Chem. 2022;65(1):163-190.

Molecular Formula C24H23N7O3S2
Molecular Weight 521.61