1187917-12-9

1187917-12-9 structure

Name: AIC-292
Chemical Name: AIC-292
CAS Number: 1187917-12-9
Molecular Formula: C₁₉H₁₂Cl₂F₂N₄O₂
Molecular Weight: 437.23
Create Date: 2022-05-09 19:34:15
Modify Date: 2024-01-14 19:14:54
AIC-292 is a potent and selective inhibitor of HIV-1 nonnucleoside reverse transcriptase. AIC-292 inhibits wild-type HIV-1 laboratory strains at low nanomolar concentrations. AIC-292 displays potent antiviral in vivo efficacy in a mouse xenograft model. AIC-292 has the potential for the research of HIV-1 infection[1].

Name	AIC-292

Description	AIC-292 is a potent and selective inhibitor of HIV-1 nonnucleoside reverse transcriptase. AIC-292 inhibits wild-type HIV-1 laboratory strains at low nanomolar concentrations. AIC-292 displays potent antiviral in vivo efficacy in a mouse xenograft model. AIC-292 has the potential for the research of HIV-1 infection[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
References	[1]. Wildum S, et al. In vitro and in vivo activities of AIC292, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor. Antimicrob Agents Chemother. 2013;57(11):5320-5329.

Molecular Formula	C₁₉H₁₂Cl₂F₂N₄O₂
Molecular Weight	437.23