AIC-292

Modify Date: 2024-01-14 19:14:54

AIC-292 Structure
AIC-292 structure
Common Name AIC-292
CAS Number 1187917-12-9 Molecular Weight 437.23
Density N/A Boiling Point N/A
Molecular Formula C19H12Cl2F2N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AIC-292


AIC-292 is a potent and selective inhibitor of HIV-1 nonnucleoside reverse transcriptase. AIC-292 inhibits wild-type HIV-1 laboratory strains at low nanomolar concentrations. AIC-292 displays potent antiviral in vivo efficacy in a mouse xenograft model. AIC-292 has the potential for the research of HIV-1 infection[1].

 Names

Name AIC-292

 AIC-292 Biological Activity

Description AIC-292 is a potent and selective inhibitor of HIV-1 nonnucleoside reverse transcriptase. AIC-292 inhibits wild-type HIV-1 laboratory strains at low nanomolar concentrations. AIC-292 displays potent antiviral in vivo efficacy in a mouse xenograft model. AIC-292 has the potential for the research of HIV-1 infection[1].
Related Catalog
References

[1]. Wildum S, et al. In vitro and in vivo activities of AIC292, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor. Antimicrob Agents Chemother. 2013;57(11):5320-5329.

 Chemical & Physical Properties

Molecular Formula C19H12Cl2F2N4O2
Molecular Weight 437.23