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2682200-93-5

2682200-93-5 structure
2682200-93-5 structure
  • Name: EGFR-IN-29
  • Chemical Name: EGFR-IN-29
  • CAS Number: 2682200-93-5
  • Molecular Formula: C36H46BrN8O2P
  • Molecular Weight: 733.68
  • Create Date: 2022-06-21 19:13:13
  • Modify Date: 2024-01-26 12:59:26
  • EGFR-IN-29 is a potent EGFR inhibitor, example J-022, extracted from Patent WO2021160087[1].

Name EGFR-IN-29
Description EGFR-IN-29 is a potent EGFR inhibitor, example J-022, extracted from Patent WO2021160087[1].
Related Catalog
Target

EGFRT790M

In Vitro EGFR-IN-29 inhibits Ba/F3 cells with stable overexpression of △19del/T790M/C797S mutant genes, cells overexpressing EGFR WT and A431 carrying EGFR WT with IC50 values of 6.8 nM, 151 nM and 1128 nM, respectively.
References

[1]. Xiangyong Liu. Quinolyl phosphine oxide compound, and composition and application thereof. Patent WO2021160087.

Molecular Formula C36H46BrN8O2P
Molecular Weight 733.68