EGFR-IN-29

Modify Date: 2024-01-26 12:59:26

EGFR-IN-29 Structure
EGFR-IN-29 structure
Common Name EGFR-IN-29
CAS Number 2682200-93-5 Molecular Weight 733.68
Density N/A Boiling Point N/A
Molecular Formula C36H46BrN8O2P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EGFR-IN-29


EGFR-IN-29 is a potent EGFR inhibitor, example J-022, extracted from Patent WO2021160087[1].

 Names

Name EGFR-IN-29

 EGFR-IN-29 Biological Activity

Description EGFR-IN-29 is a potent EGFR inhibitor, example J-022, extracted from Patent WO2021160087[1].
Related Catalog
Target

EGFRT790M

In Vitro EGFR-IN-29 inhibits Ba/F3 cells with stable overexpression of △19del/T790M/C797S mutant genes, cells overexpressing EGFR WT and A431 carrying EGFR WT with IC50 values of 6.8 nM, 151 nM and 1128 nM, respectively.
References

[1]. Xiangyong Liu. Quinolyl phosphine oxide compound, and composition and application thereof. Patent WO2021160087.

 Chemical & Physical Properties

Molecular Formula C36H46BrN8O2P
Molecular Weight 733.68