2428393-60-4

2428393-60-4 structure

Name: Corydalmine hydrochloride
Chemical Name: Corydalmine hydrochloride
CAS Number: 2428393-60-4
Molecular Formula: C₂₀H₂₄ClNO₄
Molecular Weight: 377.86
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2022-05-21 08:41:29
Modify Date: 2024-01-10 08:52:16
Corydalmine hydrochloride inhibits spore germination of some plant pathogenic as well as saprophytic fungi[1]. Corydalmine hydrochloride acts as an oral analgesic agent, exhibiting potent analgesic activity[2]. Corydalmine hydrochloride alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway[3].

Name	Corydalmine hydrochloride

Description	Corydalmine hydrochloride inhibits spore germination of some plant pathogenic as well as saprophytic fungi[1]. Corydalmine hydrochloride acts as an oral analgesic agent, exhibiting potent analgesic activity[2]. Corydalmine hydrochloride alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway[3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> GPCR/G Protein >> CXCR Signaling Pathways >> Immunology/Inflammation >> CXCR Research Areas >> Neurological Disease
In Vivo	Corydalmine hydrochloride is a potent analgesic agent, in cynomolgus monkey, beagle dog, rat and mouse liver microsomes[2].
References	[1]. Basha SA, Jha RN, Pandey VB, Singh UP. Effect of 1-corydalmine,an Alkaloid Isolated from Corydalis chaerophylla Roots on Spore Germination of Some Fungi. Mycobiology. 2007;35(2):69-71. [2]. Tang X, Di X, Zhong Z, et al. In vitro metabolism of l-corydalmine, a potent analgesic drug, in human, cynomolgus monkey, beagle dog, rat and mouse liver microsomes. J Pharm Biomed Anal. 2016;128:98-105. [3]. Zhou L, Hu Y, Li C, et al. Levo-corydalmine alleviates vincristine-induced neuropathic pain in mice by inhibiting an NF-kappa B-dependent CXCL1/CXCR2 signaling pathway. Neuropharmacology. 2018;135:34-47.

Molecular Formula	C₂₀H₂₄ClNO₄
Molecular Weight	377.86