Name | DDO-7263 |
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Description | DDO-7263, a 1,2,4-Oxadiazole derivative, is a potent Nrf2 activator. DDO-7263 upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 activates the Nrf2-ARE signaling pathway and exerts anti-inflammatory activity[1]. |
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Related Catalog | |
References |
Molecular Formula | C14H9F2N3O |
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Molecular Weight | 273.24 |