2766185-78-6

2766185-78-6 structure

Name: Mpro/PLpro-IN-1
Chemical Name: Mpro/PLpro-IN-1
CAS Number: 2766185-78-6
Molecular Formula: C₂₅H₂₇ClN₄O₃
Molecular Weight: 466.96
Catalog: Research Areas Infection
Create Date: 2022-05-31 17:59:32
Modify Date: 2024-01-04 15:28:13
Mpro/PLpro-IN-1 (Compound 29) is a potent inhibitor of Mpro/PLpro. Mpro/PLpro-IN-1 is a dual acting SARS-CoV-2 proteases inhibitor featuring micromolar inhibitory potency versus Mpro (IC50 = 1.72 μM) and submicromolar potency versus PLpro (IC50 = 0.67 μM)[1].

Name	Mpro/PLpro-IN-1

Description	Mpro/PLpro-IN-1 (Compound 29) is a potent inhibitor of Mpro/PLpro. Mpro/PLpro-IN-1 is a dual acting SARS-CoV-2 proteases inhibitor featuring micromolar inhibitory potency versus Mpro (IC50 = 1.72 μM) and submicromolar potency versus PLpro (IC50 = 0.67 μM)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Di Sarno V, et al. Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization. Eur J Med Chem. 2021;226:113863.

Molecular Formula	C₂₅H₂₇ClN₄O₃
Molecular Weight	466.96