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2400904-71-2

2400904-71-2 structure
2400904-71-2 structure
  • Name: SN38 NHS ester
  • Chemical Name: SN38 NHS ester
  • CAS Number: 2400904-71-2
  • Molecular Formula: C30H27N3O10
  • Molecular Weight: 589.55
  • Catalog: Research Areas Cancer
  • Create Date: 2022-05-24 13:15:30
  • Modify Date: 2024-02-02 20:24:44
  • SN38 NHS ester is the NHS ester derivative of SN38. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis. SN38 NHS ester can be used for the synthesis of antibody-drug conjugates (ADCs)[1].

Name SN38 NHS ester
Description SN38 NHS ester is the NHS ester derivative of SN38. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis. SN38 NHS ester can be used for the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
References

[1]. Asa Wallin, et al. Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. Oncol Rep. 2008 Jun;19(6):1493-8.

Molecular Formula C30H27N3O10
Molecular Weight 589.55