SN38 NHS ester

Modify Date: 2024-02-02 20:24:44

SN38 NHS ester Structure
SN38 NHS ester structure
Common Name SN38 NHS ester
CAS Number 2400904-71-2 Molecular Weight 589.55
Density N/A Boiling Point N/A
Molecular Formula C30H27N3O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SN38 NHS ester


SN38 NHS ester is the NHS ester derivative of SN38. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis. SN38 NHS ester can be used for the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name SN38 NHS ester

 SN38 NHS ester Biological Activity

Description SN38 NHS ester is the NHS ester derivative of SN38. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis. SN38 NHS ester can be used for the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
References

[1]. Asa Wallin, et al. Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. Oncol Rep. 2008 Jun;19(6):1493-8.

 Chemical & Physical Properties

Molecular Formula C30H27N3O10
Molecular Weight 589.55
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