2749400-35-7
2749400-35-7 structure
- Name: Bromfenac-d4 sodium
- Chemical Name: Bromfenac-d4 sodium
- CAS Number: 2749400-35-7
- Molecular Formula: C15H7D4BrNNaO3
- Molecular Weight: 360.17
- Catalog: Signaling Pathways Immunology/Inflammation COX
- Create Date: 2022-07-19 14:44:28
- Modify Date: 2024-01-09 11:28:51
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Bromfenac-d4 (sodium) is deuterium labeled Bromfenac (sodium). Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium is a brominated non-steroidal anti-inflammatory/analgesic drug (NSAID), and it is commonly used for the research of postoperative inflammation and pain following cataract surgery, and pseudophakic cystoid macular edema (CME)[1][2].
| Name | Bromfenac-d4 sodium |
|---|
| Description | Bromfenac-d4 (sodium) is deuterium labeled Bromfenac (sodium). Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium is a brominated non-steroidal anti-inflammatory/analgesic drug (NSAID), and it is commonly used for the research of postoperative inflammation and pain following cataract surgery, and pseudophakic cystoid macular edema (CME)[1][2]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Molecular Formula | C15H7D4BrNNaO3 |
|---|---|
| Molecular Weight | 360.17 |