2747915-64-4

2747915-64-4 structure
2747915-64-4 structure
  • Name: Ornidazole-d5
  • Chemical Name: Ornidazole-d5
  • CAS Number: 2747915-64-4
  • Molecular Formula: C7H5D5ClN3O3
  • Molecular Weight: 224.66
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2022-06-30 11:05:21
  • Modify Date: 2024-01-09 17:20:19
  • Ornidazole-d5 is deuterium labeled Ornidazole.

Name Ornidazole-d5
Description Ornidazole-d5 is deuterium labeled Ornidazole.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Rutgeerts, P., et al., Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology, 2005. 128(4): p. 856-61.

[3]. Goldstein, E.J., V.L. Sutter, and S.M. Finegold, Comparative susceptibilities of anaerobic bacteria to metronidazole, ornidazole, and SC-28538. Antimicrob Agents Chemother, 1978. 14(4): p. 609-13.

Molecular Formula C7H5D5ClN3O3
Molecular Weight 224.66