Name | Procaspase-6 inhibitor 13 |
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Description | Procaspase-6 inhibitor 13 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.38 uM.Procaspase-6 inhibitor 13 binds to pro-C6 at the dimer interface and contacts amino acids Y198, T199 and E214.Procaspase-6 inhibitor 13 significantly stabilizes procaspase-6. |
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References | 1. Jeremy Murray, et al. ChemMedChem. 2014 Jan;9(1):73-7, 2. |
Molecular Formula | C16H14FN5O |
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Molecular Weight | 311.32 |