303985-05-9

303985-05-9 structure

303985-05-9 structure

Name: BET-IN-7
Chemical Name: BET-IN-7
CAS Number: 303985-05-9
Molecular Formula: C₁₈H₁₂ClN₃OS
Molecular Weight: 353.83
Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
Create Date: 2022-07-11 20:49:23
Modify Date: 2024-01-08 13:24:03
BET-IN-7 (Compound 1) is a potent inhibitor of BET with a Ki and Kd of 12.27 and 89.3 μM, respectively. BET-IN-7 has the potential for the research of sepsis[1].

Name	BET-IN-7

Description	BET-IN-7 (Compound 1) is a potent inhibitor of BET with a Ki and Kd of 12.27 and 89.3 μM, respectively. BET-IN-7 has the potential for the research of sepsis[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
References	[1]. Chen X, et al. Discovery of 2-((2-methylbenzyl)thio)-6-oxo-4-(3,4,5-trimethoxyphenyl)-1,6-dihydropyrimidine-5-carbonitrile as a novel and effective bromodomain and extra-terminal (BET) inhibitor for the treatment of sepsis. Eur J Med Chem. 2022 May 8;238:114423

Molecular Formula	C₁₈H₁₂ClN₃OS
Molecular Weight	353.83