2761259-22-5

2761259-22-5 structure

Name: PDGFRα/FLT3-ITD-IN-3
Chemical Name: PDGFRα/FLT3-ITD-IN-3
CAS Number: 2761259-22-5
Molecular Formula: C₂₆H₃₉N₉
Molecular Weight: 477.65
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FLT3
Create Date: 2022-07-01 16:59:13
Modify Date: 2024-02-13 19:25:46
PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of 0.153 and 0.004 μM, respectively. PDGFRα/FLT3-ITD-IN-3 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].

Name	PDGFRα/FLT3-ITD-IN-3

Description	PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of 0.153 and 0.004 μM, respectively. PDGFRα/FLT3-ITD-IN-3 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3
References	[1]. Vlková K, et al. Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors. Bioorg Med Chem Lett. 2022 Mar 15;60:128603

Molecular Formula	C₂₆H₃₉N₉
Molecular Weight	477.65