2761259-09-8

2761259-09-8 structure

Name: PDGFRα/FLT3-ITD-IN-2
Chemical Name: PDGFRα/FLT3-ITD-IN-2
CAS Number: 2761259-09-8
Molecular Formula: C₂₈H₄₁N₉O
Molecular Weight: 519.68
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FLT3
Create Date: 2022-08-16 19:25:30
Modify Date: 2024-04-06 17:34:58
PDGFRα/FLT3-ITD-IN-2 (Compound 13d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 20 and 1.654 μM, respectively. PDGFRα/FLT3-ITD-IN-2 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].

Name	PDGFRα/FLT3-ITD-IN-2

Description	PDGFRα/FLT3-ITD-IN-2 (Compound 13d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 20 and 1.654 μM, respectively. PDGFRα/FLT3-ITD-IN-2 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3
References	[1]. Vlková K, et al. Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors. Bioorg Med Chem Lett. 2022 Mar 15;60:128603

Molecular Formula	C₂₈H₄₁N₉O
Molecular Weight	519.68