2380227-06-3

2380227-06-3 structure

Name: PPARγ agonist 4
Chemical Name: PPARγ agonist 4
CAS Number: 2380227-06-3
Molecular Formula: C₂₄H₂₂FN₃O
Molecular Weight: 387.45
Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
Create Date: 2022-07-01 23:56:57
Modify Date: 2024-01-02 07:48:40
PPARγ agonist 4 (Compound 18b) is a potent and selective agonist of PPARγ. PPARγ agonist 4 is not cytotoxic neither on non-resistant nor on resistant cells. PPARγ agonist 4 exerts antitumor potency only in combination with Imatinib[1].

Name	PPARγ agonist 4

Description	PPARγ agonist 4 (Compound 18b) is a potent and selective agonist of PPARγ. PPARγ agonist 4 is not cytotoxic neither on non-resistant nor on resistant cells. PPARγ agonist 4 exerts antitumor potency only in combination with Imatinib[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR
References	[1]. Schoepf AM, et al. Overcoming imatinib resistance in chronic myelogenous leukemia cells using non-cytotoxic cell death modulators. Eur J Med Chem. 2020 Jan 1;185:111748.

Molecular Formula	C₂₄H₂₂FN₃O
Molecular Weight	387.45