2350219-22-4

2350219-22-4 structure

2350219-22-4 structure

Name: ACC1/2-IN-1
Chemical Name: ACC1/2-IN-1
CAS Number: 2350219-22-4
Molecular Formula: C₃₄H₃₂N₄O₄
Molecular Weight: 560.64
Catalog: Signaling Pathways Metabolic Enzyme/Protease Acetyl-CoA Carboxylase
Create Date: 2022-08-08 16:30:58
Modify Date: 2024-01-17 13:44:27
ACC1/2-IN-1 (compound 4s) is a potent ACC1/2 inhibitor with IC50 values of 98.06 and 29.43 nM for ACC1 and ACC2, respectively. ACC1/2-IN-1 can be used for cancer research[1].

Name	ACC1/2-IN-1

Description	ACC1/2-IN-1 (compound 4s) is a potent ACC1/2 inhibitor with IC50 values of 98.06 and 29.43 nM for ACC1 and ACC2, respectively. ACC1/2-IN-1 can be used for cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Acetyl-CoA Carboxylase
In Vitro	ACC1/2-IN-1 (compound 4s) (72 hours; tumor cell lines) has anti-proliferative activity against A549, H1975, HCT116 and H7901 cell lines with IC50 values of 0.578, 1.005, 0.680 and 1.406 μΜ, respectively[1].
References	[1]. Wei Q, et al. Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors. Bioorg Chem. 2020 Aug;101:103943.

Molecular Formula	C₃₄H₃₂N₄O₄
Molecular Weight	560.64