2460167-51-3

2460167-51-3 structure

2460167-51-3 structure

Name: Anticancer agent 72
Chemical Name: Anticancer agent 72
CAS Number: 2460167-51-3
Molecular Formula: C₂₀H₁₉N₇O₂
Molecular Weight: 389.41
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-09-06 09:10:28
Modify Date: 2024-04-08 14:12:22
Anticancer agent 72 (compound 8c) is a potent inhibitor of K+ channel. Anticancer agent 72 induces apoptosis[1].

Name	Anticancer agent 72

Description	Anticancer agent 72 (compound 8c) is a potent inhibitor of K+ channel. Anticancer agent 72 induces apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
In Vitro	Anticancer agent 72 (compound 8c) has an inhibitory effects against PC3, MCF-7, HeLa, SKBr3 and A549 cells with IC50 values of 17.58, 5.55, 0.54, 11.13 and 20.40 μM[1].
References	[1]. Romero AH, et al. Anticancer potential of new 3-nitroaryl-6-(N-methyl)piperazin-1,2,4-triazolo[3,4-a]phthalazines targeting voltage-gated K+ channel: Copper-catalyzed one-pot synthesis from 4-chloro-1-phthalazinyl-arylhydrazones. Bioorg Chem. 2020 Aug;101:104031.

Molecular Formula	C₂₀H₁₉N₇O₂
Molecular Weight	389.41