2353417-85-1

2353417-85-1 structure

2353417-85-1 structure

Name: PROTAC VEGFR-2 degrader-2
Chemical Name: PROTAC VEGFR-2 degrader-2
CAS Number: 2353417-85-1
Molecular Formula: C₅₀H₅₆FN₉O₆S
Molecular Weight: 930.10
Catalog: Signaling Pathways PROTAC PROTAC
Create Date: 2022-08-17 06:36:33
Modify Date: 2024-01-11 08:34:39
PROTAC VEGFR-2 degrader-2（PROTAC-4）, a PROTAC VEGFR-2 degrader, exhibits little VEGFR-2 inhibition (IC50> 1 μM) and anti-proliferative activity against EA.hy926 cells (IC50> 100μM)[1].

Name	PROTAC VEGFR-2 degrader-2

Description	PROTAC VEGFR-2 degrader-2（PROTAC-4）, a PROTAC VEGFR-2 degrader, exhibits little VEGFR-2 inhibition (IC50> 1 μM) and anti-proliferative activity against EA.hy926 cells (IC50> 100μM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
References	[1]. Yuanyuan Shan, et al. Discovery of novel anti-angiogenesis agents. Part 11: Development of PROTACs based on active molecules with potency of promoting vascular normalization. Eur J Med Chem. 2020 Nov 1;205:112654.

Molecular Formula	C₅₀H₅₆FN₉O₆S
Molecular Weight	930.10