Name | tert-butyl N-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate |
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Synonyms |
19-Amino-5,8,11,14,17-pentaoxa-2-azanonadecanoic Acid 1,1-Dimethylethyl Ester
Boc-NH-PEG5-CH2CH2NH2 t-boc-N-amido-PEG5-Amine |
Description | PROTAC Linker 17 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 17 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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Related Catalog | |
Target |
Alkyl/ether |
References |
Molecular Formula | C17H36N2O7 |
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Molecular Weight | 380.47700 |
Exact Mass | 380.25200 |
PSA | 113.99000 |
LogP | 1.45750 |
Hazard Codes | Xi |
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~99% 189209-27-6 |
Literature: Gerard, Estelle; Meulle, Aline; Feron, Olivier; Marchand-Brynaert, Jacqueline Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 586 - 590 |
~% 189209-27-6 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
~% 189209-27-6 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
~% 189209-27-6 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
~% 189209-27-6 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
~% 189209-27-6 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
~% 189209-27-6 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
~% 189209-27-6 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
~% 189209-27-6 |
Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |