2085274-00-4

2085274-00-4 structure

2085274-00-4 structure

Name: Antifungal agent 35
Chemical Name: Antifungal agent 35
CAS Number: 2085274-00-4
Molecular Formula: C₂₆H₂₇BrN₄O₄
Molecular Weight: 539.42
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2022-09-12 21:31:26
Modify Date: 2024-04-03 17:40:23
Antifungal agent 35 (compound 24) is a potent antifungal agent. Antifungal agent 35 is a potent enhancer of antifungal activity of Fluconazole against C. albicans[1].

Name	Antifungal agent 35

Description	Antifungal agent 35 (compound 24) is a potent antifungal agent. Antifungal agent 35 is a potent enhancer of antifungal activity of Fluconazole against C. albicans[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
In Vitro	Antifungal agent 35 (compound 24) (0.0015-15 mM; C. albicans) inhibits fungal cell growth in a dose-dependent manner with EC50 value of 0.001 µM in the presence of fluconazole[1]. Antifungal agent 35 (compound 24) (0.0015-15 mM; C. albicans) shows potent activities (EC50 < 1 μM) against all resistant isolates in the presence of fluconazole[1].
References	[1]. Mood AD, et, al. Potent Antifungal Synergy of Phthalazinone and Isoquinolones with Azoles Against Candida albicans. ACS Med Chem Lett. 2017 Jan 11;8(2):168-173.

Molecular Formula	C₂₆H₂₇BrN₄O₄
Molecular Weight	539.42