2091950-43-3

2091950-43-3 structure
2091950-43-3 structure
  • Name: Multi-kinase-IN-3
  • Chemical Name: Multi-kinase-IN-3
  • CAS Number: 2091950-43-3
  • Molecular Formula: C33H33N5O3
  • Molecular Weight: 547.65
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK PDGFR
  • Create Date: 2022-08-31 20:26:29
  • Modify Date: 2024-07-20 19:57:29
  • Multi-kinase-IN-3 (compound 2) is a potent angiokinase inhibitor. Multi-kinase-IN-3 shows inhibition activity against VEGFR-2 and PDGFRβ, with IC50 values of 58.3 and 55 nM, respectively[1].

Name Multi-kinase-IN-3
Description Multi-kinase-IN-3 (compound 2) is a potent angiokinase inhibitor. Multi-kinase-IN-3 shows inhibition activity against VEGFR-2 and PDGFRβ, with IC50 values of 58.3 and 55 nM, respectively[1].
Related Catalog
Target

PDGFRβ:55 ± 2.6 nM (IC50)

VEGFR-2:58.3 ± 5.9 nM (IC50)

References

[1]. Qin M, et al. Structural modifications of indolinones bearing a pyrrole moiety and discovery of a multi-kinase inhibitor with potent antitumor activity. Bioorg Med Chem. 2020 Jun 1;28(11):115486.

Molecular Formula C33H33N5O3
Molecular Weight 547.65