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1164275-01-7

1164275-01-7 structure
1164275-01-7 structure
  • Name: Duocarmycin analog-2
  • Chemical Name: Duocarmycin analog-2
  • CAS Number: 1164275-01-7
  • Molecular Formula: C29H23ClN4O3
  • Molecular Weight: 510.97
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA Alkylator/Crosslinker
  • Create Date: 2022-10-12 19:12:54
  • Modify Date: 2024-04-03 10:26:11
  • Duocarmycin analog-2 is a potent DNA alkylating agent. Duocarmycin analog-2 can be used of synthetic immunoconjugate. Duocarmycin analog-2 has antitumor activity[1].

Name Duocarmycin analog-2
Description Duocarmycin analog-2 is a potent DNA alkylating agent. Duocarmycin analog-2 can be used of synthetic immunoconjugate. Duocarmycin analog-2 has antitumor activity[1].
Related Catalog
In Vitro Duocarmycin analog-2 (72 h) has anti-proliferative activity with IC50 values of 0.001, 0.002, 0.002, 0.004, 0.009, 0.01, 0.015, 0.019, 0.019, 0.019, 0.02, 0.04, and 0.068 nM for DU4475, SET2, HCT 16, A2780, MDA MB468, LNCaP, LS174T, CCRF-CEM, COLO205, H2087, H661, A549, and MCD MB231 cells, respectively.
References

[1]. Chowdari NS, et, al. Enediyne compounds, conjugates thereof, and uses and methods therefor. WO2013122823A1.

Molecular Formula C29H23ClN4O3
Molecular Weight 510.97