186610-88-8
186610-88-8 structure
- Name: hVEGF-IN-2
- Chemical Name: way-607500
- CAS Number: 186610-88-8
- Molecular Formula: C19H18N2O2
- Molecular Weight: 306.37
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
- Create Date: 2022-11-21 14:52:58
- Modify Date: 2024-01-10 18:52:53
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hVEGF-IN-2 (compound 19) is a selective VEGF (Flk-1) receptor tyrosine kinases (RTK) inhibitor with an IC50 value of 2.5 μM. hVEGF-IN-2 inhibits PDGF RTK activity with an IC50 value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific drugs[1].
| Name | way-607500 |
|---|
| Description | hVEGF-IN-2 (compound 19) is a selective VEGF (Flk-1) receptor tyrosine kinases (RTK) inhibitor with an IC50 value of 2.5 μM. hVEGF-IN-2 inhibits PDGF RTK activity with an IC50 value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific drugs[1]. |
|---|---|
| Related Catalog | |
| Target |
VEGFR1:2.5 μM (IC50) PDGF:33.1 μM (IC50) |
| In Vitro | hVEGF-IN-2 (0-100 μM) shows the inhibitory activities to particular RTKs at the cellular level with IC50 values of 2.5, 33.1, ＞100, ＞100 and ＞100 nM for VEGF, PDGF, EGF, HER-2 and IGF-1, respectively[1]. |
| Molecular Formula | C19H18N2O2 |
|---|---|
| Molecular Weight | 306.37 |