hVEGF-IN-2

Modify Date: 2024-01-10 18:52:53

hVEGF-IN-2 Structure
hVEGF-IN-2 structure
Common Name hVEGF-IN-2
CAS Number 186610-88-8 Molecular Weight 306.37
Density N/A Boiling Point N/A
Molecular Formula C19H18N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of hVEGF-IN-2


hVEGF-IN-2 (compound 19) is a selective VEGF (Flk-1) receptor tyrosine kinases (RTK) inhibitor with an IC50 value of 2.5 μM. hVEGF-IN-2 inhibits PDGF RTK activity with an IC50 value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific drugs[1].

 Names

Name way-607500

 hVEGF-IN-2 Biological Activity

Description hVEGF-IN-2 (compound 19) is a selective VEGF (Flk-1) receptor tyrosine kinases (RTK) inhibitor with an IC50 value of 2.5 μM. hVEGF-IN-2 inhibits PDGF RTK activity with an IC50 value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific drugs[1].
Related Catalog
Target

VEGFR1:2.5 μM (IC50)

PDGF:33.1 μM (IC50)

In Vitro hVEGF-IN-2 (0-100 μM) shows the inhibitory activities to particular RTKs at the cellular level with IC50 values of 2.5, 33.1, >100, >100 and >100 nM for VEGF, PDGF, EGF, HER-2 and IGF-1, respectively[1].

 Chemical & Physical Properties

Molecular Formula C19H18N2O2
Molecular Weight 306.37