502654-40-2

502654-40-2 structure

Name: CYP4A11/CYP4F2-IN-1
Chemical Name: CYP4A11/CYP4F2-IN-1
CAS Number: 502654-40-2
Molecular Formula: C₁₅H₁₅N₃OS
Molecular Weight: 285.36
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
Create Date: 2022-12-07 12:08:45
Modify Date: 2024-01-18 10:13:01
CYP4A11/CYP4F2-IN-1 is a potent dual inhibitor of cytochrome P450 (CYP) 4A11 and CYP4F2, with IC50s of 19 nM and 17 nM, respectively. CYP4A11/CYP4F2-IN-1 has potential for the research of renal diseases[1].

Name	CYP4A11/CYP4F2-IN-1

Description	CYP4A11/CYP4F2-IN-1 is a potent dual inhibitor of cytochrome P450 (CYP) 4A11 and CYP4F2, with IC50s of 19 nM and 17 nM, respectively. CYP4A11/CYP4F2-IN-1 has potential for the research of renal diseases[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Metabolic Disease
Target	CYP4A11:19 nM (IC50) CYP4F2:17 nM (IC50)
In Vitro	CYP4A11/CYP4F2-IN-1 (compound 2) inhibits 20-Hydroxyeicosatetraenoic acid (20-HETE) production from arachidonic acid in human renal microsomes, with an IC50 of 4.2 nM[1].

Molecular Formula	C₁₅H₁₅N₃OS
Molecular Weight	285.36