142828-10-2

142828-10-2 structure

142828-10-2 structure

Name: Autocamtide-3
Chemical Name: Autocamtide-3
CAS Number: 142828-10-2
Molecular Formula: C₆₅H₁₁₃N₂₁O₂₀
Molecular Weight: 1508.72
Catalog: Signaling Pathways Neuronal Signaling CaMK
Create Date: 2023-01-22 14:36:33
Modify Date: 2024-04-11 15:11:25
Autocamtide-3, a 13-amino-acid peptide containing Thr287, is a selective CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK) substrate[1].

Name	Autocamtide-3

Description	Autocamtide-3, a 13-amino-acid peptide containing Thr287, is a selective CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK) substrate[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> CaMK Research Areas >> Neurological Disease
Target	CaMK II
In Vitro	20 μM Autocamtide-3 (H2N-Lys-Lys-Ala-Leu-His-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-COOH), and 5 μL of CaMKII is used in a 50 μL kinase-assay reaction. Autocamtide-3 shows catalytic activity[1].
References	[1]. Mehtap Yilmaz, et al. Phosphorylation at Ser²⁶ in the ATP-binding site of Ca²⁺/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity. Biosci Rep. 2013 Feb 7;33(2):e00024.

Molecular Formula	C₆₅H₁₁₃N₂₁O₂₀
Molecular Weight	1508.72