Name | CYP1B1-IN-5 |
---|
Description | CYP1B1-IN-5 (Compound 6q) is a potent and selective cytochrome P450 1B1 (CYP1B1) inhibitor with an IC50 of 4.7 nM[1]. |
---|---|
Related Catalog | |
Target |
CYP1B1:4.7 nM (IC50) CYP1A1:190.7 nM (IC50) CYP1A2:585.7 nM (IC50) |
In Vitro | CYP1B1-IN-5 (Compound 6q) 通过与残基 Phe231、Phe134 和血红素形成 π-π 叠加相互作用,与 CYP1B1 的结合口袋结合[1]。 |
References |
Molecular Formula | C14H8INO2 |
---|---|
Molecular Weight | 349.12 |