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51481-65-3

51481-65-3 structure
51481-65-3 structure
  • Name: Mezlocillin
  • Chemical Name: mezlocillin
  • CAS Number: 51481-65-3
  • Molecular Formula: C21H25N5O8S2
  • Molecular Weight: 539.582
  • Catalog: API Antibiotics Penicillin
  • Create Date: 2018-09-10 15:50:19
  • Modify Date: 2024-01-08 13:10:29
  • Mezlocillin (BAY-f 1353) is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin is active against both gram-negative and gram-positive bacteria. Mezlocillin can be used in bacterial infection research[1][2].

Name mezlocillin
Synonyms 6R-[2-[3-(Methylsulfonyl)-2-oxo-1-imidazolidine Carboxamido]-2-phenylacetamido]penicillanic Acid
EINECS 257-233-8
(2S,5R,6R)-3,3-Dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
[2S-[2a,5a,6b(S*)]]-3,3-Dimethyl-6-[[[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[(2R)-2-[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]-2-phenylacetyl]amino]-7-oxo-, (2S,5R,6R)-
(2S,5R,6R)-3,3-Dimethyl-6-((R)-2-(3-(methylsulfonyl)-2-oxo-1-imidazolidinecarboxamido)-2-phenylacetamido)-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
Antibiotic bay-f 1353
Mezlocillin
Meloxacam acid
MFCD00056866
Melocillin sodium
antibioticbay-f1353
Multocillin
Bay f 1353
(2S,5R,6R)-3,3-Dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-3,3-Dimethyl-6-((R)-2-(3-(methylsulfonyl)-2-oxo-1-imidazolidinecarboxamido)-2-phenylacetamido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
Description Mezlocillin (BAY-f 1353) is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin is active against both gram-negative and gram-positive bacteria. Mezlocillin can be used in bacterial infection research[1][2].
Related Catalog
In Vivo Mezlocillin (subcutaneous injection; 1.7-5.7 mg/kg; twice daily; 7 d) treatment in vivo suppresses the IgM and IgG responses and the delayed-type hypersensitivity reaction, observes the loss of hair, and inhibits lymphocyte proliferation of animals treated with all doses[1]. Animal Model: Male Balb/c mice[1] Dosage: 1.7, 4.3, and 5.7 mg/kg Administration: Subcutaneous injection; 1.7, 4.3, and 5.7 mg/kg; twice daily; 7 days Result: Suppressed the IgM and IgG responses and the delayed-type hypersensitivity reaction treated with all doses. Observed a loss of hair in the majority of animals treated with all doses. Inhibited lymphocyte proliferation of spleen-cell cultures from animals.
Density 1.6±0.1 g/cm3
Boiling Point 655.5ºC at 760 mmHg
Molecular Formula C21H25N5O8S2
Molecular Weight 539.582
Flash Point 350.2ºC
Exact Mass 539.114441
PSA 207.18000
LogP -1.18
Index of Refraction 1.701
Precursor  2

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